top of page
NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) 500mgNicotinamide Adenine Dinucleotide 500mg

 

What is NAD+?

 

Nicotinamide Adenine Dinucleotide (NAD+) is a crucial coenzyme found in all living cells, integral to various biological processes. It plays a central role in energy metabolism, enabling cells to convert nutrients from food into usable energy, particularly vital for the brain and other essential organs. NAD+ is also indispensable for DNA repair, reducing inflammation, and regulating genes associated with aging. Without sufficient NAD+, cells would be unable to maintain proper function, leading to impaired cellular health and overall vitality .

 

The Importance of NAD+ in Anti-Aging Medicine

NAD+ therapy represents a cutting-edge approach in anti-aging medicine. As we age, our body's NAD+ levels naturally decline, further exacerbated by lifestyle factors such as poor diet, excessive alcohol and drug consumption, chronic stress, and exposure to environmental toxins. This decline significantly contributes to the aging process and the manifestation of various aging signs, both internal and external .

Benefits of NAD+ Therapy

Slowing Down Cellular Aging:
NAD+ activates specific enzymes like sirtuins, which are crucial for DNA repair and cellular protection. Sirtuins play a significant role in maintaining cellular integrity and function, thereby slowing down the cellular aging process and preserving overall cell health .

Improving Metabolism and Weight Management:
NAD+ enhances metabolic processes, aiding in better weight management and increased energy levels. This helps counteract the natural tendency to gain weight with age, promoting a healthier and more active lifestyle .

Enhancing Mental Clarity and Cognitive Function:
Optimal NAD+ levels are linked to improved mental clarity, concentration, and overall cognitive function. Maintaining high NAD+ levels supports better memory, decision-making, and brain power, even as one ages .

Increasing Energy and Endurance:
By promoting a healthy cellular balance, NAD+ combats fatigue and boosts energy levels. This leads to improved motivation, physical performance, and overall quality of life .

Repairing Sun Damage:
NAD+ plays a key role in repairing cells damaged by UV rays, reducing risks of pigmentation, fine lines, and skin cancer. This makes NAD+ therapy beneficial for skin health and appearance, helping to maintain youthful and healthy skin .

Reducing Inflammation:
NAD+ activates specific enzymes that help prevent and repair damage caused by inflammation. This contributes to overall better health by reducing the risk of chronic diseases linked to inflammation .

Enhancing Stress Resilience:
NAD+ strengthens the body's ability to manage stress by promoting antioxidant production and improving the biological response to environmental stressors. This enhances resilience to physical and mental stress, supporting better long-term health .

By adopting NAD+ therapy, individuals can take a decisive step towards healthy aging. The proven benefits for vitality and overall well-being make NAD+ an essential component in the pursuit of a longer, healthier life .

References

  • Imai, S., & Guarente, L. (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology, 24(8), 464-471.
  • Verdin, E. (2015). NAD+ in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208-1213.
  • Yoshino, J., Baur, J. A., & Imai, S. (2018). NAD+ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism, 27(3), 513-528.
  • Sinclair, D. A., & LaPlante, M. D. (2019). Lifespan: Why we age and why we don't have to. Atria Books.
  • Mouchiroud, L., Houtkooper, R. H., & Auwerx, J. (2013). NAD+ metabolism: A therapeutic target for age-related metabolic disease. Nature Reviews Drug Discovery, 12(8), 466-481.
  • Cantó, C., & Auwerx, J. (2012). NAD+ as a signaling molecule modulating metabolism. Cold Spring Harbor Perspectives in Medicine, 2(7), a016222.
  • Vonderwalde, I., & Divito, S. (2018). NAD+ repletion: The current therapeutic landscape. Biochemistry and Cell Biology, 96(3), 225-239.
  • Zhu, X. H., Lu, M., Lee, B. Y., Ugurbil, K., & Chen, W. (2015). In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proceedings of the National Academy of Sciences, 112(9), 2876-2881.
  • Liu, L., Su, X., Quinn, W. J., Hui, S., Krukenberg, K., Frederick, D. W., Redpath, P., Zhan, L., Chellappa, K., White, E., Migaud, M. E., Mitchison, T. J., & Baur, J. A. (2018). Quantitative analysis of NAD synthesis-breakdown fluxes. Cell Metabolism, 27(5), 1067-1080.
  • Gano, L. B., Donato, A. J., & Pasha, M. A. (2014). The effects of short-term supplementation with the NAD+ precursor nicotinamide riboside on the age-related susceptibility of the liver to ischemia-reperfusion injury. Aging Cell, 13(4), 517-518.
  • Covarrubias, A. J., Perrone, R., Grozio, A., & Verdin, E. (2021). NAD+ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology, 22(2), 119-141.
  • Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic potential of NAD-boosting molecules: The in vivo evidence. Cell Metabolism, 27(3), 529-547.

NAD+ (Nicotinamide Adenine Dinucleotide) 500mg

119,00 €Preis
    bottom of page