โก MOTS-c 10MGโ Mitochondrial-Derived Research Peptide Involved in Cellular Metabolism and Adaptation
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide discovered in recent years and encoded within mitochondrial DNA ๐งฌ. Unlike conventional peptides encoded by nuclear DNA, MOTS-c originates from the mitochondrial genome, making it a molecule of significant scientific interest in the study of cellular energy regulation and metabolic signaling.
Current knowledge regarding MOTS-c is based primarily on preclinical and experimental research, conducted within controlled laboratory environments.
๐ฌ Mitochondrial Function and Energy Regulation
MOTS-c has been studied for its role in cellular energy homeostasis. As mitochondria are central to ATP production and metabolic regulation, this peptide has attracted attention in research focused on:
Cellular energy balance
Metabolic stress adaptation
Mitochondria-to-nucleus communication
Experimental findings suggest that MOTS-c may act as an adaptive signaling molecule, enabling cells to respond to fluctuations in energy availability โ๏ธ.
๐ฅ Glucose Metabolism and Insulin Sensitivity (Experimental Context)
In laboratory and animal models, MOTS-c has been investigated for its potential involvement in:
Regulation of glucose metabolism
Modulation of cellular insulin sensitivity
Adaptation to nutritional and metabolic stress
These observations have positioned MOTS-c as a peptide of interest in metabolic and cellular physiology research ๐.
๐ง Cellular Signaling Pathways and Gene Expression
MOTS-c has also been associated with the activation of key intracellular signaling pathways, particularly those involved in:
Cellular stress responses
Regulation of gene expression
Long-term metabolic adaptation
Some experimental studies indicate that MOTS-c may translocate to the cell nucleus under specific conditions, contributing to mitochondria-nucleus signaling mechanisms ๐งฉ.
๐ก๏ธ Research on Cellular Resilience and Aging Mechanisms
Within fundamental research, MOTS-c is further explored for its potential association with:
Cellular resilience and stress resistance
Metabolic stability over time
Aging-related cellular adaptation
These research directions have placed MOTS-c among peptides of interest in studies related to mitochondrial biology and cellular aging โณ.
๐ Scientific Interest and Research Applications
Due to its unique mitochondrial origin and multifunctional biological profile, MOTS-c is studied across several research domains, including:
Mitochondrial biology
Energy metabolism
Cellular signaling pathways
Metabolic stress and adaptation
Its characteristics support its use exclusively as a research compound in specialized laboratory settings ๐งช.
๐ Conclusion
Although MOTS-c is not approved for medical or therapeutic use, available preclinical data highlight its scientific relevance in the study of mitochondrial signaling and metabolic regulation. Its potential role in energy balance and cellular adaptation continues to drive ongoing investigation in basic research.
๐ Scientific References (Selection)
Lee, C. et al. โ MOTS-c: A mitochondrial-derived peptide that regulates metabolic homeostasis
Kim, K. H. et al. โ Mitochondrial peptides and energy regulation in experimental models
Reynolds, J. C. et al. โ MOTS-c and cellular adaptation to metabolic stress
Journals of mitochondrial biology and cellular metabolism
(References provided for scientific context only)
โ ๏ธ Important Regulatory Notice (EU Compliance)
This content is provided for informational and educational purposes only ๐.
MOTS-c is not intended for human or animal use ๐ซ, nor for diagnostic, therapeutic, or preventive purposes.
This product is strictly intended for laboratory research and investigative use only and must be handled exclusively by qualified professionals in controlled research environments.
This product is not a medicinal product, not a food supplement, and has not been approved by regulatory authorities such as the EMA.
