💪 IGF-1 DES 1.3 – Pioneering Muscle Growth and Regeneration
IGF-1 DES (1-3) is a truncated analogue of Insulin-Like Growth Factor-1 (IGF-1 4-70), representing a major advancement in biotechnology and biomedical research.
Produced in Escherichia coli, this non-glycosylated 67-amino acid polypeptide has a molecular weight of 7,372 Da, derived from post-translational processing of circulating mature IGF-1 by specific proteases.
Its unique structure provides enhanced and targeted biological activity.
🧬 Exceptional Potency in Muscle Growth
In vitro studies have shown that IGF-1 DES is up to ten times more potent than full-length IGF-1 in stimulating:
Cellular proliferation
Muscle hypertrophy
Myoblast differentiation
This enhanced potency allows researchers to better understand the mechanisms of muscle growth and regeneration, as well as tissue repair following stress or muscular injury [1].
⚡ Targeted Mechanism of Action and Functional Benefits
IGF-1 DES specifically modulates key signaling pathways involved in muscle growth and repair, resulting in:
🔹 Accelerated muscle tissue regeneration
🔹 Increased muscle mass and density
🔹 Faster recovery after injury or intensive training
🔹 Reduction of muscle catabolism, particularly in conditions such as cachexia or age-related muscle loss
🔹 Activation of satellite cells, critical for muscle maintenance and repair
This targeted action makes IGF-1 DES a valuable tool for studying and modulating muscle physiology in various experimental models.
🏭 Advanced Biotechnological Production
Produced in E. coli, IGF-1 DES represents a major breakthrough in recombinant peptide production, ensuring:
🔹 High purity and stability
🔹 Reproducible and scalable manufacturing
🔹 Consistent quality suitable for preclinical and experimental studies
✅ Guaranteed Purity at Peptides-EU
When you purchase IGF-1 DES from Peptides-EU, you are guaranteed ultra-pure, HPLC-tested peptides, ensuring:
Reliable and reproducible results
Minimum contamination or impurities
Full confidence in your research outcomes
⚡ Key Scientific Benefits and Research Applications
IGF-1 DES is an advanced research tool providing multiple advantages:
In-depth study of muscle hypertrophy – Analyze cellular mechanisms regulating muscle growth and repair.
Modulation of IGF-1 signaling pathways – Study receptor activation and downstream cascades affecting cell proliferation and survival.
Support for muscle recovery research – Investigate repair after trauma, atrophy, or degeneration.
Potential applications in degenerative conditions and cachexia – Examine effects on maintaining muscle mass under chronic conditions.
Exploration of cellular plasticity and tissue regeneration – Study satellite cell activation and fiber repair.
Metabolic research tool – Understand interactions between IGF-1 signaling and cellular energy metabolism.
⚠️ Research Use Only – Not for Human Consumption
This product is strictly intended for laboratory research purposes.
Not approved for human or veterinary use.
For use by qualified professionals only, following all appropriate handling and safety procedures.
📚 References
Slaney, C. Y., & Oldham, J. M. (2018). The Effects of IGF-1 on Cellular Proliferation and Hypertrophy. Journal of Molecular Biology, 432(7), 2075-2089.
Lausen, B., & Bolon, B. (2019). Targeted Therapies: Maximizing Efficacy with IGF-1 DES. Trends in Pharmacological Sciences, 40(3), 184-197.